个人简介
2008年12月份获得工学博士学位,2011年10月至2013年8月,在加拿大麦吉尔大学做访问教授。主要从事高效串联反应、H2O2 选择性氧化等绿色催化合成方面的研究工作,在环境友好反应介质绿色过程替代等方面具有较好的研究积累。目前主持国家自然科学基金面上项目1项、企业委托项目1项,主持完成国家自然科学基金3项、国家重点研发计划子课题1项、企业委托课题3项、陕西省自然科学基金1项、西安市工业应用技术研究项目1项、太阳集团tyc151中央高校基本科研业务费3项,参与完成国家自然科学基金重点项目一项(第二参与人)。在 J. Am. Chem. Soc.、Angew Chem. Int. Ed.、Org. Lett.、Adv. Synth. Catal.、Chem.Eur. J.、J. Org. Chem. 等本领域主流学术期刊发表研究论文50 余篇,申请中国发明专利10件,其中授权5 件,获陕西省高等学校科学技术奖一等奖(2016 年,第二完成人)和陕西省科学技术奖二等奖(2016 年,第二完成人)。主编《有机化学实验》,参编《有机化学学习指导与习题详解》和《中级有机化学》。
研究方向:绿色催化合成。
研究兴趣:(1) 过渡金属催化碳氢键活化的高效串联反应;(2)离子液体的合成及其应用。
代表性论文
1. Zhuang-Zhuang Li, Wan-Di Li, Juan Fan, Jun-Ting Li, Zhong-Wen Liu, Xian-Ying Shi *, Silver trifluoroacetate as a bifunctional reagent for palladium-catalyzed oxidative carbonylative [4 + 1] annulation of aromatic acids, Org. Chem. Front., 2023, 10, 2243–2250.
2. Yu-Zhu Wang, Zhuang-Zhuang Li, Zhong-Wen Liu, Xian-Ying Shi*, Heterogenous carboxyl-functionalized bilayer ionic liquids/polyoxometalate catalysts for extractant-free oxidative desulfurization, J. Mol. Liq., 2023, 373, 121245.
3. Wen-Ting Wei, Zhuang-Zhuang Li, Wan-Di Li, Jia-Qi Li, Xian-Ying Shi*, A green method for constructing phthalidesvia oxidative coupling of aromatic acids and acrylates in neat water and air, Chinese J. Org. Chem., 2023, 43, 1177-1186. (邀请文章,中国女科学家专辑).
4. Xin-Ran Li+, Wan-Di Li+, Wen-Ting Wei, Juan Fan, Zhong-Wen Liu, Xian-Ying Shi*, Sequential cobalt/rhodium-catalyzed tandem cyclization of aromatic aldehydes with acrylates for preparing 3-substituted phthalides in oxygen atmosphere and neat water, Asian J. Org. Chem., 2022, 11, e202100725.
5. Xin-Ran Li, Si-Qi Chen, Juan Fan, Chao-Jun Li, Xue Wang, Zhong-Wen Liu, Xian-Ying Shi*, Controllable tandem [3+2] cyclization of aromatic aldehydes with maleimides: rhodium(III)-catalyzed divergent synthesis of indane-fused pyrrolidine-2,5-dione, Org. Lett., 2020, 22, 8808−8813.
6. Si-Qi Chen, Xin-Ran Li, Chao-Jun Li, Juan Fan, Zhong-Wen Liu, Xian-Ying Shi*, Aldehyde as a traceless directing group for regioselective C−H alkylation catalyzed by rhodium(III) in air, Org. Lett., 2020, 22, 1259−1264.
7. Fan Pu, Zhong-Wen Liu, Lin-Yan Zhang, Juan Fan, Xian-Ying Shi*, Switchable C−H alkylation of aromatic acids with maleimides in water: carboxyl as a diverse directing group, ChemCatChem, 2019, 11, 4116–4122 (邀请文章,女性催化专辑).
8. Jia-Ni Wang, Si-Qi Chen, Zhong-Wen Liu, Xian-Ying Shi*, Divergent syntheses of spiroindanones and 2‑substituted 1‑indanones by ruthenium-catalyzed tandem coupling and cyclization of aromatic acids with α,β-unsaturated ketones, J. Org. Chem., 2019, 84, 1348−1362
9. Wen-Jing Han, Fan Pu, Chao-Jun Li, Zhong-Wen Liu, Juan Fan, Xian-Ying Shi*, Carboxyl-directed conjugate addition of C-H bonds to α,β-unsaturated ketones in air and water, Adv. Synth. Catal., 2018, 360, 1358−1363.
10. Fan Pu, Lin-Yan Zhang, Zhong-Wen Liu, Xian-Ying Shi*, Palladium(II)-catalyzed decarboxylative cross-dehydrogenative coupling: direct synthesis of meta-substituted biaryls from aromatic acids, Adv. Synth. Catal., 2018, 360, 2644−2649.
11. Juan Fan, Peng-Min Wang, Jia-Ni Wang, Xue Zhao, Zhong-Wen Liu, Jun-Fa Wei, Xian-Ying Shi*, Ruthenium (II)-catalyzed synthesis of phthalides via the cascade addition and cyclization of aromatic acids with aldehydes, Sci. China Chem., 2018, 61, 153−158.
12. Wen-Jing Han, Fan Pu, Juan Fan, Zhong-Wen Liu, Xian-Ying Shi*, Rhodium(III)-catalyzed tandem C−H olefination and oxidative cyclization of aromatic acids with acrylates for the synthesis of (E)-3- ylidenephthalides, Adv. Synth. Catal., 2017, 359, 3520−3525.
13. Peng-Min Wang, Fan Pu, Ke-Yan Liu, Chao-Jun Li, Zhong-Wen Liu, Xian-Ying Shi*, Juan Fan, Ming-Yu Yang, Jun-Fa Wei, Catalyst-free three-component tandem CDC cyclization: convenient access to isoindolinones from aromatic acid, amides, and DMSO by a pummerer-type rearrangement, Chem. Eur. J., 2016, 22, 6262−6267.
14. Xian-Ying Shi*, Wen-Jing Han, Chao-Jun Li*, Transition-metal-catalyzed direct addition of aryl C–H bonds to unsaturated electrophiles, Chem. Rec., 2016, 16, 1178−1190.
15. Xian-Ying Shi*, Ke-Yan Liu, Juan Fan, Xue-Fen Dong, Jun-Fa Wei, Chao-Jun Li*, A convenient synthesis of N-aryl benzamides by rhodium-catalyzed ortho-amidation and decarboxylation of benzoic acids, Chem. Eur. J., 2015, 21, 1900−1903.
16. Xian-Ying Shi*, Xue-Fen Dong, Juan Fan, Ke-Yan Liu, Jun-Fa Wei, Chao-Jun Li*, Ru(II)-catalyzed ortho-amidation and decarboxylation of aromatic acids: a versatile route to meta-substituted N-aryl benzamides, Sci. China. Chem., 2015, 58, 1286−1291.